Correct reporting and interpretation of clinical data

Improving the reporting and interpretation of clinical trial outcomes.

Serum 25-hydroxyvitamin D immunoassays: recommendations for correct clinical interpretation.

assay on the Roche Modular analyzer. They used clinical samples that were almost free of 25hydroxyvitamin D2 (25-OH-D2) ( 10 nmol/L) as confirmed by liquid chromatography–tandem mass spectrometry (LC-MS/MS) and found a good overall agreement between the results obtained with the Roche assay and those measured with the DiaSorin RIA and by LC-MS/MS. Although they acknowledged that the Roche assay...

An Algorithm for Modeling and Interpretation of Seismoelectric Data

Generally speaking, seismoelectric modeling is a prospecting method based on seismic and electromagnetic waves, in which waves generated by a seismic source at the boundary of the two environments generate a relative fluid-solid motion formed as a result of antagonism between the elastic properties of the environment with the saturated fluid. This research has as its objective, a study of the e...

Reporting cerebrospinal fluid data: knowledge base and interpretation software.

The compilation of cerebrospinal fluid (CSF) patient data together with a graphic display of immunoglobulin patterns in a single CSF report has two main advantages: analytical and clinical plausibility control of a complex set of data improves quality assessment and allows improved clinical specificity and sensitivity for recognition of disease-related "typical" data patterns. The widespread us...

Discussion Required for Correct Interpretation

Khush Mittal I read the paper by Chi et al. with interest. The authors found a greater hypoxia response gene expression in carcinomas than stromal cells grown in vitro, but were not sure of the underlying explanation (see Discussion in [1]). The underlying explanation may be the difference in mitotic activity and hence metabolic activity between these two cell types, such that hypoxia may be pr...